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COL4A5

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen
Protein class

Cancer-related genes, Disease related genes, Human disease related genes

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enriched (Oligodendrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HeLa, HHSteC, HUVEC TERT2, TIME)

Interaction

There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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