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COL5A1

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Anti-COL5A1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


COL5A1 (Collagen Type V Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL5A1 include Ehlers-Danlos Syndrome, Classic Type, 1 and Ehlers-Danlos Syndrome Type 2. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include heparin binding and extracellular matrix structural constituent. An important paralog of this gene is COL11A1.
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Endometrial stromal cells, Fibroblasts, Skeletal myocytes, Leydig cells, Smooth muscle cells, Sertoli cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BJ, fHDF/TERT166, HeLa, HHSteC, SiHa)

Interaction

Trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Interacts with CSPG4.

Molecular function

Heparin-binding

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