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CRADD

Anti-CRADD Products

AbPlus™ Anti-CRADD Magnetic Beads (VS-0724-YC225) (VS-0724-YC225)
- Target: CRADD
- Target Species: Human
- Application: IP, Protein Purification
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Recombinant Mouse anti-Human CRADD Monoclonal antibody (EML2017) (MOB-1766CT)
- Species Reactivity: Human
- Application: WB
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Anti-CRADD Immunohistochemistry Kit (VS-0325-XY536)
- Species Reactivity: Human, Mouse, Rat
- Target: CRADD
- Application: IHC
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Hi-Affi™ Rabbit Anti-CRADD Recombinant Antibody (clone DS798AB) (MOR-0798)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, ICC, IHC-P, IP, WB
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For Research Use Only. Not For Clinical Use.

CRADD (CASP2 And RIPK1 Domain Containing Adaptor With Death Domain) is a Protein Coding gene. Diseases associated with CRADD include Mental Retardation, Autosomal Recessive 34, With Variant Lissencephaly and Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Apoptosis Modulation and Signaling and Apoptosis and survival Caspase cascade. Gene Ontology (GO) annotations related to this gene include protease binding and death domain binding.

Protein class

Cancer-related genes, Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells, Early spermatids, Astrocytes, Inhibitory neurons)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Forms a complex named the PIDDosome with PIDD1 and CASP2 (PubMed:9044836, PubMed:8985253, PubMed:15073321, PubMed:16652156, PubMed:17159900, PubMed:17289572). Interacts (via Death domain) with RIPK1 (via Death domain); the interaction is direct (PubMed:9044836). Interacts with TRADD (PubMed:8985253). Interacts with TNFRSF1A (PubMed:8985253).

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