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CRTAM
Loading...Anti-CRTAM Products
- Mouse Anti-CRTAM Recombinant Antibody (clone 17B2) (HPAB-1089-FY)
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- Derivation: Chimeric (hamster/mouse)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, FC
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- Human Anti-CRTAM Recombinant Antibody (VS-0723-WK71) (VS-0723-WK71)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
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- Human Anti-CRTAM Recombinant Antibody (VS-0723-WK81) (VS-0723-WK81)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
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- Hamster Anti-CRTAM Recombinant Antibody (clone 17B2); scFv Fragment (HPAB-1089-FY-F(E))
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- Species Reactivity: Human
- Type: Hamster scFv
- Application: WB, FC
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- Mouse Anti-CRTAM Recombinant Antibody (clone 17B2); Fab Fragment (HPAB-1089-FY-S(P))
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- Derivation: Chimeric (hamster/mouse)
- Species Reactivity: Human
- Type: Chimeric(hamster/mouse) Fab
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.
Background
CRTAM (Cytotoxic And Regulatory T Cell Molecule) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include receptor binding. An important paralog of this gene is CADM1.
Protein class
CD markers
Predicted location
Membrane
Single cell type specificity
Group enriched (dendritic cells, T-cells, Plasma cells)
Immune cell specificity
Immune cell enhanced (NK-cell)
Cell line specificity
Cell line enriched (SCLC-21H)
Interaction
Monomer (PubMed:23583034). May form homodimer (via Ig-like V-type domain) (PubMed:23583034, PubMed:23871486). Interacts (via Ig-like V-type domain) with CADM1 (via Ig-like V-type domain); the interaction competes with CRTAM homodimerization and CADM1 homodimerization (PubMed:15781451, PubMed:15811952, PubMed:23871486). Interacts (via PDZ-binding motif) with SCRIB (via PDZ domain 3); the interaction promotes CRTAM and SCRIB polarization in a subset of CD4+ T-cells (By similarity).
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