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CSTA

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For Research Use Only. Not For Clinical Use.


Background

CSTA (Cystatin A) is a Protein Coding gene. Diseases associated with CSTA include Peeling Skin Syndrome 4 and Peeling Skin Syndrome 2. Among its related pathways are Keratinization and Developmental Biology. Gene Ontology (GO) annotations related to this gene include structural molecule activity and protein binding, bridging. An important paralog of this gene is CSTB.
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Squamous epithelial cells, Basal respiratory cells, monocytes, Club cells, Kupffer cells)

Immune cell specificity

Group enriched (classical monocyte, myeloid DC, intermediate monocyte, neutrophil, non-classical monocyte)

Cell line specificity

Cell line enhanced (HBEC3-KT, hTCEpi, THP-1, U-698, U-937)

Molecular function

Protease inhibitor, Thiol protease inhibitor

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