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CXCR5

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Anti-CXCR5 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


CXCR5 encodes a receptor for the chemokines CXCL13, which is involved in the migration and organization of B cells and T follicular helper cells within lymphoid tissues. CXCR5 is crucial for the formation of B cell follicles in secondary lymphoid organs, such as the spleen and lymph nodes, and plays a vital role in immune surveillance. Mutations in CXCR5 can lead to defects in immune responses, particularly in the formation of germinal centers, which are important for antibody production and the defense against infections.
Protein class

CD markers, G-protein coupled receptors

Predicted location

Membrane

Single cell type specificity

Cell type enriched (B-cells)

Immune cell specificity

Group enriched (naive B-cell, memory B-cell)

Cell line specificity

Group enriched (Daudi, U-698)

Molecular function

G-protein coupled receptor, Receptor, Transducer

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