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CCKBR
This gene encodes a G protein-coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
Protein class
Cancer-related genes, FDA approved drug targets, G-protein coupled receptors
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (Granulosa cells, Excitatory neurons, Gastric mucus-secreting cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (NTERA-2)
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, IF, IP
- Mouse Anti-Cckbr Antibody, mRNA (AGTO-G003E-mRNA)
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- Species Reactivity: Mouse
- Anti-Cckbr immunotoxin (scFv)-PE (AGTO-G003E)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
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For Research Use Only. Not For Clinical Use.