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CHRDL1

This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein class

Disease related genes, Human disease related genes

Predicted location

Secreted

Single cell type specificity

Group enriched (Fibroblasts, Muller glia cells, Astrocytes, Leydig cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (ASC diff, ASC TERT1, hTERT-RPE1)

Molecular function

Developmental protein

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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