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CTAGE5
The protein encoded by this gene is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. Autoantibodies against the encoded protein have been found in some cancers. Several transcript variants encoding different isoforms have been found for this gene.
Protein class
Disease related genes, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Endometrial ciliated cells, Proximal tubular cells, Collecting duct cells, Ductal cells, Exocrine glandular cells, Pancreatic endocrine cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (CAPAN-2)
Interaction
Interacts with MIA3 (PubMed:21525241, PubMed:25202031, PubMed:27138255, PubMed:27170179). Interacts with the COPII coat subunits SEC23A, SEC23B and maybe SEC24C (PubMed:21525241, PubMed:27551091). Interacts with PREB; recruits PREB to endoplasmic reticulum exit sites (PubMed:25202031, PubMed:27170179). Interacts with APOB (PubMed:27138255).
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
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For Research Use Only. Not For Clinical Use.