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DCAF12
Loading...Anti-DCAF12 Products
- Chicken Anti-TCC52 Polyclonal IgY (BRD-0788MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: ICC, WB
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- Anti-DCAF12 Immunohistochemistry Kit (VS-0325-XY625)
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- Species Reactivity: Human, Mouse, Rat
- Target: DCAF12
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Erythroid cells, Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the DCX(DCAF12) E3 ubiquitin ligase complex, at least composed of CUL4 (CUL4A or CUL4B), DDB1, DCAF12 and RBX1.
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