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Background

Dengue virus (DENV), a member of the family Flaviviridae, is a mosquito-borne pathogen with four distinct serotypes including DENV-1 to DENV-4. Currently, it is estimated that DENV infects about 390 million cases globally each year, resulting in 96 million cases clinically apparent from mild fever to dengue hemorrhagic fever (DHF) or the life-threatening dengue shock syndrome (DSS).
DENV
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