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DLGAP1

Anti-DLGAP1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


DLGAP1 (DLG Associated Protein 1) is a Protein Coding gene. It is predicted to enable molecular adaptor activity and is a structural constituent of postsynaptic density. It is involved in several processes, including aggresome assembly; regulation of postsynaptic neurotransmitter receptor activity; and regulation of proteasomal protein catabolic process. Diseases associated with DLGAP1 include Retinitis Pigmentosa 55 and Transient Tic Disorder.
Predicted location

Intracellular

Single cell type specificity

Group enriched (Inhibitory neurons, Excitatory neurons, Oligodendrocyte precursor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (Daudi, HAP1, U-2197, U-87 MG)

Interaction

Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1 (By similarity). Interacts with MPP2 (via the SH3-Guanylate kinase-like sub-module) (By similarity).

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