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EDA

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Anti-EDA Products

    • Target: extra domains A (EDA)
    • Linker: Disulfide-linker
    • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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For Research Use Only. Not For Clinical Use.


Background

The anti-EDA1 monoclonal antibodies may be used in the treatment of disorders relating to excessive action of EDA1 such as hirsutism, ectopic teeth, hyperhidrosis, breast TME-targeting Antibody, dermal eccrine cylindroma or skin disorders such as sebaceous gland hyperplasia, comedones, milia, acne, seborrhea, rosacea, steatoma, and furuncles. The anti-EDA1 antibodies are also useful in immunoassays such as sandwich ELISA.
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Microglial cells, Oligodendrocytes, Oligodendrocyte precursor cells)

Immune cell specificity

Immune cell enhanced (MAIT T-cell, intermediate monocyte)

Cell line specificity

Cell line enhanced (EFO-21, Hep G2, OE19, RPMI-8226)

Interaction

Homotrimer. The homotrimers may then dimerize and form higher-order oligomers.

Molecular function

Developmental protein

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