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EEF1A2

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For Research Use Only. Not For Clinical Use.


This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
Protein class

Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Horizontal cells, Bipolar cells, Cardiomyocytes, Rod photoreceptor cells, Skeletal myocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HAP1, MCF7, SCLC-21H, T-47d, U-2 OS)

Interaction

Monomer.

Molecular function

Elongation factor

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