


EFNA5

Anti-EFNA5 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, IP
- Chicken Anti-Ephrin-A5 Polyclonal IgY (BRD-0193MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
Cancer-related genes, RAS pathway related proteins
Membrane
Group enriched (Excitatory neurons, Inhibitory neurons, Astrocytes)
Immune cell enhanced (gdT-cell)
Cell line enhanced (AF22, RPTEC TERT1)
Binds to EPHB2. Interacts with EPHA8; activates EPHA8 (By similarity). Binds to the receptor tyrosine kinases EPHA2, EPHA3 and EPHB1. Forms a ternary EFNA5-EPHA3-ADAM10 complex mediating EFNA5 extracellular domain shedding by ADAM10 which regulates the EFNA5-EPHA3 complex internalization and function.
Developmental protein