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EGFR
Loading...Anti-EGFR Products
- A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer (MHC-LC773)
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- Class: Class I
- Antigen: EGFR
- Antigen Species: Human
- Peptide: YLNTVQPTCV
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Related Diseases
Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
Related Signaling Pathways
JAK-STAT Signaling Pathway
