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EPX

Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Excitatory neurons, Inhibitory neurons, Oligodendrocytes, Microglial cells)

Immune cell specificity

Immune cell enriched (eosinophil)

Cell line specificity

Cell line enriched (NB-4)

Interaction

Tetramer of two light chains and two heavy chains.

Molecular function

Oxidoreductase, Peroxidase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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