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ERBB2 & CD3

Anti-ERBB2 & CD3 Products
- Mouse Anti-NHP CD3 Recombinant Antibody (clone SK7) (VS-1024-XY89)
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- Species Reactivity: Human, Non-human primate
- Type: Mouse IgG1, kappa
- Application: IHC, FC
- Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) (TAB-0416CL)
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- Application: FC, IB, ELISA
- Humanized Anti-Human CD3 Recombinant Antibody (TAB-0418CL)
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- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (HPAB-0551-WJ) (HPAB-0551-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (HPAB-0550-WJ) (HPAB-0550-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Cyt, Inhib
- Human Anti-CD3 Recombinant Antibody (HPAB-0549-WJ) (HPAB-0549-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Cyt, Inhib
- Human Anti-CD3 Recombinant Antibody (HPAB-0548-WJ) (HPAB-0548-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA
- Human Anti-CD3 Recombinant Antibody (HPAB-0547-WJ) (HPAB-0547-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Cyt, Inhib
- Human Anti-CD3 Recombinant Antibody (clone HuM291) (HPAB-0546-WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: Inhib, FC
- Human Anti-CD3 Recombinant Antibody (HPAB-1103-CN) (HPAB-1103-CN)
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- Species Reactivity: Monkey
- Type: Humanized IgG1
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (HPAB-1102-CN) (HPAB-1102-CN)
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- Species Reactivity: Monkey
- Type: Humanized IgG1
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (HPAB-1101-CN) (HPAB-1101-CN)
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- Species Reactivity: Monkey
- Type: Humanized IgG1
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (clone M291) (HPAB-0545-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Cyt, Inhib
- Human Anti-CD3 Recombinant Antibody (clone HuYTH 12.5) (HPAB-0544-WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (clone YTH 12.5) (HPAB-0543-WJ)
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- Species Reactivity: Human
- Type: Rat IgG2b
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (HPAB-0555-WJ) (HPAB-0555-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Cyt, Inhib
- Human Anti-CD3 Recombinant Antibody (HPAB-0554-WJ) (HPAB-0554-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, FuncS
- Human Anti-CD3 Recombinant Antibody (HPAB-0553-WJ) (HPAB-0553-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (HPAB-0552-WJ) (HPAB-0552-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone hc3E3) (HPAB-0442-YJ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (clone m3E3) (HPAB-0441-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC
- Mouse Anti-CD3 Antibody (clone G3(3)), mRNA (FAMAB-0053YC-mRNA)
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- Species Reactivity: Human
- Mouse Anti-CD3 Antibody (clone FN18), mRNA (FAMAB-0044CQ-mRNA)
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- Species Reactivity: Rhesus
- Rat Anti-CD3 Antibody (clone Dow2), mRNA (TAB-0365CL-mRNA)
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- Species Reactivity: Mouse
- Human Anti-CD3 Antibody (clone hc3E3), mRNA (HPAB-0442-YJ-mRNA)
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- Species Reactivity: Human
- Mouse Anti-CD3 Antibody (clone m3E3), mRNA (HPAB-0441-YJ-mRNA)
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- Species Reactivity: Human
- Human Anti-CD3 Antibody, mRNA (TAB-0417CL-mRNA)
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- Species Reactivity: Human
- Human Anti-CD3 Agonistic Antibody (VS-0724-XY16) (VS-0724-XY16)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Agonistic assays
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Fab fragment
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone CBLC-007) (HPAB-1181WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Rat Anti-CD3 Recombinant Antibody (clone 17A2) (MOB-0202MC)
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, IHC, IP, Activ, CMCD, Depletion
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IF, ELISA
- Human Anti-CD3 Recombinant Antibody (clone h1D10) (HPAB-1527WJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FC
- Mouse Anti-CD3 Recombinant Antibody (clone 1D10) (HPAB-1526WJ)
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Hamster Anti-CD3 Recombinant Antibody (HPAB-M0469-YC) (HPAB-M0469-YC)
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- Species Reactivity: Mouse
- Type: Hamster IgG
- Application: FuncS
- Mouse Anti-CD3 Recombinant Antibody (HPAB-M0468-YC) (HPAB-M0468-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
- Human Anti-CD3 Recombinant Antibody (HPAB-M0466-YC) (HPAB-M0466-YC)
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus
- Type: Humanized IgG
- Application: FC
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- Species Reactivity: Mouse, Rat
- Type: Mouse IgG3, κ
- Application: FC, FuncS, IHC, IF, IP
- Human Anti-CD3 Recombinant Antibody (HPAB-1909LY) (HPAB-1909LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC
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- Species Reactivity: Chimpanzee, Human
- Type: Mouse IgG1, κ
- Application: FC, FuncS, IF, IHC-Fr, IHC
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-1909LY-S(P)) (HPAB-1909LY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scfv
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (clone CBLC-007); scFv Fragment (HPAB-1181WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Hamster Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-M0469-YC-S(P)) (HPAB-M0469-YC-S(P))
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- Species Reactivity: Mouse
- Type: Hamster scFv
- Application: FuncS
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-1103-CN-S(P)) (HPAB-1103-CN-S(P))
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- Species Reactivity: Monkey
- Type: Humanized scFv
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-1102-CN-S(P)) (HPAB-1102-CN-S(P))
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- Species Reactivity: Monkey
- Type: Humanized scFv
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-1101-CN-S(P)) (HPAB-1101-CN-S(P))
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- Species Reactivity: Monkey
- Type: Humanized scFv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (clone hc3E3); scFv Fragment (HPAB-0442-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (clone m3E3); scFv Fragment (HPAB-0441-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (clone h1D10) (HPAB-1527WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB, FC
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (clone 1D10) (HPAB-1526WJ-S(P))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0549-WJ-S(P)) (HPAB-0549-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0548-WJ-S(P)) (HPAB-0548-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0547-WJ-S(P)) (HPAB-0547-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone HuM291); scFv Fragment (HPAB-0546-WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (clone M291); scFv Fragment (HPAB-0545-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone HuYTH 12.5); scFv Fragment (HPAB-0544-WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0555-WJ-S(P)) (HPAB-0555-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0554-WJ-S(P)) (HPAB-0554-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0553-WJ-S(P)) (HPAB-0553-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0552-WJ-S(P)) (HPAB-0552-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0551-WJ-S(P)) (HPAB-0551-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (HPAB-0550-WJ-S(P)) (HPAB-0550-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (clone YTH 12.5); scFv Fragment (HPAB-0543-WJ-S(P))
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- Species Reactivity: Human
- Type: Rat IgG2b
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-1103-CN-F(E)) (HPAB-1103-CN-F(E))
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- Species Reactivity: Monkey
- Type: Humanized Fab
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-1102-CN-F(E)) (HPAB-1102-CN-F(E))
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- Species Reactivity: Monkey
- Type: Humanized Fab
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-1101-CN-F(E)) (HPAB-1101-CN-F(E))
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- Species Reactivity: Monkey
- Type: Humanized Fab
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (clone HuYTH 12.5); Fab Fragment (HPAB-0544-WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (clone YTH 12.5); Fab Fragment (HPAB-0543-WJ-F(E))
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- Species Reactivity: Human
- Type: Rat IgG2b
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0550-WJ-F(E)) (HPAB-0550-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0549-WJ-F(E)) (HPAB-0549-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0548-WJ-F(E)) (HPAB-0548-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0547-WJ-F(E)) (HPAB-0547-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone HuM291); Fab Fragment (HPAB-0546-WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (clone M291); Fab Fragment (HPAB-0545-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0555-WJ-F(E)) (HPAB-0555-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0554-WJ-F(E)) (HPAB-0554-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0553-WJ-F(E)) (HPAB-0553-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0552-WJ-F(E)) (HPAB-0552-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0551-WJ-F(E)) (HPAB-0551-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone CBLC-007); Fab Fragment (HPAB-1181WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (clone hc3E3); Fab Fragment (HPAB-0442-YJ-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (clone m3E3); Fab Fragment (HPAB-0441-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (clone h1D10) (HPAB-1527WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, FC
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (clone 1D10) (HPAB-1526WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Hamster Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-M0469-YC-F(E)) (HPAB-M0469-YC-F(E))
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- Species Reactivity: Mouse
- Type: Hamster Fab
- Application: FuncS
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-M0468-YC-F(E)) (HPAB-M0468-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Human Anti-CD3 Recombinant Antibody Fab Fragment (HPAB-M0467-YC-F(E)) (HPAB-M0467-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-M0466-YC-F(E)) (HPAB-M0466-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus
- Type: Humanized Fab
- Application: FC
- Human Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-1909LY-F(E)) (HPAB-1909LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC
- Recombinant Camelid Anti-CD3 Single Domain Antibody (HPAB-1029WJ)
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA
- Anti-Mouse CD3 Recombinant Antibody (Dow2) (TAB-0365CL)
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- Application: FC, IHC
- Mouse Anti-CD3 Recombinant Antibody (TAB-0422CL) (TAB-0422CL)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA
- Anti-CD3 Immunohistochemistry Kit (VS-0325-XY360)
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- Species Reactivity: Human
- Target: CD3
- Application: IHC
- Human Anti-CD3 (clone YTH 12.5) scFv-Fc Chimera (VS-0125-FY56)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: ELISA, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ICC
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- Antibody Host: Mouse
- Antibody Reactivity: Human
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.