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Fap

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The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

Target:
FAP
Linker:
AO-Mc-
Drug:
MMAE (Monomethyl auristatin E)
Target:
FAP
Linker:
MC-PABC (maleimidocaproyl-p-aminobenzoyloxycarbonyl)
Drug:
MMAE (Monomethyl auristatin E)
Target:
FAP
Linker:
AO-Mc-
Drug:
MMAE (Monomethyl auristatin E)
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Targets:
FAP & CD3e
Type:
BiTE
Application:
FC, ELISA
Targets:
FAP & CD3e
Type:
BiTE
Application:
FC, ELISA
Targets:
FAP & CD3e
Type:
BiTE
Application:
FC, ELISA
Targets:
FAP & CD3e
Type:
BiTE
Application:
FC, ELISA
Targets:
FAP & CD3e
Type:
BiTE
Application:
FC, ELISA
Targets:
FAP & CD3e
Type:
BiTE
Application:
FC, ELISA
Targets:
FAP & CD3e
Type:
BiTE
Application:
FC, ELISA
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, ELISA, IHC, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, RIA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
FC, RIA, Biosensors, FuncS
Targets:
FAP & CD3
Type:
BiTE
Application:
FuncS, Promising therapeutic agent
Targets:
DR5 & FAP
Type:
F(ab')2
Application:
FuncS, Promising therapeutic agent
Target:
FAP
Species Reactivity:
Human
Cytokine 1:
IL10
Host:
Human
Cytokine 1 Species:
Human
Molecule Class:
IgG1-IL10
Target:
FAP
Species Reactivity:
Human
Cytokine 1:
IL10
Host:
Human
Cytokine 1 Species:
Human
Molecule Class:
Fab-IL10
Target:
FAP
Species Reactivity:
Human
Cytokine 1:
IL10
Host:
Human
Cytokine 1 Species:
Human
Molecule Class:
IgG1-IL10
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