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FCRLA
Anti-FCRLA Recombinant Antibody Products
- Anti-FCRLA immunotoxin E9 (IgG)-RTA (AGTO-G027R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Anti-FCRLA immunotoxin E9 (IgG)-PE (AGTO-G027E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Anti-FCRLA immunotoxin E9 (scFv)-RTA (AGTO-G026R)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Anti-FCRLA immunotoxin E9 (scFv)-PE (AGTO-G026E)
-
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
Compare
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (B-cells, Melanocytes)
Immune cell specificity
Group enriched (memory B-cell, naive B-cell)
Cell line specificity
Group enriched (Daudi, SK-MEL-30, U-698)
Interaction
Monomer or homodimer; disulfide-linked.
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