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FGFR4
Loading...Anti-FGFR4 Products
- Mouse Anti-FGFR4 Recombinant Antibody (clone LD1); scFv Fragment (NS-028CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB, FC, IHC, IP
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- Derivation: Phage display
- Species Reactivity: Human, Mouse
- Type: Human Antibody
- Application: ELISA, FC
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- Anti-Human FGFR4 Recombinant Antibody Fab Fragment (XPA.48.056) (TAB-066WM-F(E))
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- Derivation: Phage display
- Species Reactivity: Human, Mouse
- Type: Human Antibody
- Application: ELISA, FC
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- Anti-Human FGFR4 Recombinant Antibody scFv Fragment (XPA.48.056) (TAB-066WM-S(P))
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- Derivation: Phage display
- Species Reactivity: Human, Mouse
- Type: Human Antibody
- Application: ELISA, FC
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- Human Anti-FGFR4 Recombinant Antibody (HPAB-0054-LS) (HPAB-0054-LS)
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Human IgG
- Application: Inhib
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- Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-384CQ-F(E)) (TAB-384CQ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Anti-Human FGFR4 Recombinant Antibody (TAB-286CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC, ELISA
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- A*02:01/Human FGFR4 (ALLAGLVSL) MHC Pentamer (MHC-YF433)
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- Class: Class I
- Antigen: FGFR4
- Antigen Species: Human
- Peptide: ALLAGLVSL
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.148) (HPAB-0058-LS)
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: Inhib, ELISA, WB
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- Human Anti-FGFR4 Antibody, mRNA (TAB-286CL-mRNA)
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- Species Reactivity: Human
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- Human Anti-FGFR4 Recombinant Antibody (clone BM1) (HPAB-0059-LS)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA, WB
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- Human Anti-FGFR4 Recombinant Antibody (clone BM2) (HPAB-0060-LS)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA, WB
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- Human Anti-FGFR4 Recombinant Antibody (clone BM3) (HPAB-0061-LS)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA, WB
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- Human Anti-FGFR4 Recombinant Antibody (clone BM4) (HPAB-0062-LS)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA, WB
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- Human Anti-FGFR4 Recombinant Antibody (HPAB-0069-LS) (HPAB-0069-LS)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC, Inhib
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- Human Anti-FGFR4 Recombinant Antibody (VS-0723-WK114) (VS-0723-WK114)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
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- Mouse Anti-FGFR4 Recombinant Antibody (VS-0224-XY48) (VS-0224-XY48)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: ELISA, WB, FC, IF, IP, IHC
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- AbPlus™ Anti-FGFR4 Magnetic Beads (F85-6C5) (VS-0424-XY103)
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- Target: FGFR4
- Target Species: Human
- Application: IP, Protein Purification
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- Human Anti-FGFR4 Recombinant Antibody (HPAB-0056-LS) (HPAB-0056-LS)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib
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- Human Anti-FGFR4 Recombinant Antibody (HPAB-0055-LS) (HPAB-0055-LS)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib
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- Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.117) (HPAB-0057-LS)
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: Inhib, ELISA, WB
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- Human Anti-FGFR4 Recombinant Antibody (HPAB-0442-FY) (HPAB-0442-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib
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- Mouse Anti-FGFR4 Recombinant Antibody (HPAB-2922LY) (HPAB-2922LY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-2922LY-S(P)) (HPAB-2922LY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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- Mouse Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-2922LY-F(E)) (HPAB-2922LY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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- Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0055-LS-S(P)) (HPAB-0055-LS-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
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- Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0442-FY-S(P)) (HPAB-0442-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
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- Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0442-FY-F(E)) (HPAB-0442-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
Compare
- Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0054-LS-S(P)) (HPAB-0054-LS-S(P))
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Human scFv
- Application: Inhib
Compare
- Mouse Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-068WM-F(E)) (TAB-068WM-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB
Compare
- Mouse Anti-FGFR4 Recombinant Antibody (clone LD1); Fab Fragment (NS-028CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB, FC, IHC, IP
Compare
- Rat Anti-FGFR4 Recombinant Antibody (TAB-069WM) (TAB-069WM)
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- Species Reactivity: Human
- Type: Rat IgG
- Application: ELISA, WB, FC, Inhib
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- Rat Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-069WM-F(E)) (TAB-069WM-F(E))
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- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, WB, FC
Compare
- Rat Anti-FGFR4 Recombinant Antibody; scFv Fragment (TAB-069WM-S(P)) (TAB-069WM-S(P))
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- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, WB, FC
Compare
- Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0056-LS-S(P)) (HPAB-0056-LS-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.117); scFv Fragment (HPAB-0057-LS-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.148); scFv Fragment (HPAB-0058-LS-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM1); scFv Fragment (HPAB-0059-LS-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM2); scFv Fragment (HPAB-0060-LS-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM3); scFv Fragment (HPAB-0061-LS-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM4); scFv Fragment (HPAB-0062-LS-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0069-LS-S(P)) (HPAB-0069-LS-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC, Inhib
Compare
- Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0054-LS-F(E)) (HPAB-0054-LS-F(E))
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- Species Reactivity: Human, Mouse, Rat, Monkey
- Type: Human Fab
- Application: Inhib
Compare
- Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0055-LS-F(E)) (HPAB-0055-LS-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
Compare
- Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0056-LS-F(E)) (HPAB-0056-LS-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.117); Fab Fragment (HPAB-0057-LS-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.148); Fab Fragment (HPAB-0058-LS-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM1); Fab Fragment (HPAB-0059-LS-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM2); Fab Fragment (HPAB-0060-LS-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM3); Fab Fragment (HPAB-0061-LS-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody (clone BM4); Fab Fragment (HPAB-0062-LS-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA, WB
Compare
- Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0069-LS-F(E)) (HPAB-0069-LS-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, Inhib
Compare
- Mouse Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-065WM-F(E)) (TAB-065WM-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, FC
Compare
- Anti-Human FGFR4 Recombinant Antibody (F85-6C5) (TAB-067WM)
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- Species Reactivity: Human
- Application: IP, ELISA
Compare
- Anti-Human FGFR4 Recombinant Antibody Fab Fragment (F85-6C5) (TAB-067WM-F(E))
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- Species Reactivity: Human
- Application: ELISA
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- Anti-Human FGFR4 Recombinant Antibody scFv Fragment (F85-6C5) (TAB-067WM-S(P))
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- Species Reactivity: Human
- Application: ELISA
Compare
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human
- Target: FGFR4
- Host Animal: Rat
- Application: ELISA, FC, Inhib, Cell-uptake
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- Anti-FGFR4 Immunohistochemistry Kit (VS-0525-XY2545)
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- Species Reactivity: Human
- Target: FGFR4
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
Protein class
Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, RAS pathway related proteins, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Skeletal myocytes, Cholangiocytes, Undifferentiated cells, Theca cells, Hepatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (CACO-2, Hep G2, RH-30)
Interaction
Monomer. Homodimer after ligand binding. Interacts with FGF1, FGF2, FGF4, FGF6, FGF8, FGF9, FGF16, FGF17, FGF18, FGF19, FGF21 and FGF23 (in vitro). Binding affinity for FGF family members is enhanced by interactions between FGFs and heparan sulfate proteoglycans. Interacts with KLB; this strongly increases the affinity for FGF19 and FGF23. Affinity for FGF19 is strongly increased by KLB and sulfated glycosaminoglycans. KLB and KL both interact with the core-glycosylated FGFR4 in the endoplasmic reticulum and promote its degradation, so that only FGFR4 with fully mature N-glycans is expressed at the cell surface. Identified in a complex with NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts with MMP14 and HIP1 (PubMed:11433297, PubMed:16597617, PubMed:17623664, PubMed:18670643, PubMed:20683963, PubMed:20798051, PubMed:21653700, PubMed:7518429, PubMed:8663044). Interacts with STAT3 (PubMed:26675719).
Molecular function
Kinase, Receptor, Transferase, Tyrosine-protein kinase
More Types Infomation
Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance