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FKBP3

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Anti-FKBP3 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]
Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Late spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Molecular function

Isomerase, Rotamase

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