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FLI1
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Microglial cells, NK-cells, Kupffer cells, Endothelial cells, monocytes, B-cells, Hepatic stellate cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HEL, HUVEC TERT2, REH, TIME)
Interaction
Can form homodimers or heterodimers with ETV6/TEL1.
Molecular function
Activator, DNA-binding
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF
- Recombinant Mouse Anti-Human FLI1 Antibody (MOB-1524MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
-
- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-P
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB
- Mouse Anti-FLI1 Recombinant Antibody (VS3-WK843) (VS3-WK843)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.