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FZD5

Anti-FZD5 Products

Human Anti-FZD5 Recombinant Antibody (PABJ-0145) (PABJ-0145)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, FuncS
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Human Anti-FZD5 Antibody (PABJ-0145-mRNA), mRNA (PABJ-0145-mRNA)
- Species Reactivity: Human
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Rabbit Anti-FZD5 Polyclonal Antibody (MRO-1876-CN) (MRO-1876-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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Recombinant Mouse anti-Human FZD5 Monoclonal antibody (EML2242) (MOB-0749CT)
- Species Reactivity: Human
- Application: WB
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Mouse Anti-FZD5 Recombinant Antibody (clone 2D12) (VS3-QX453)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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Human Anti-FZD5 Recombinant Antibody scFv Fragment (PABJ-0145-S(P)) (PABJ-0145-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Inhib, FuncS
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Human Anti-FZD5 Recombinant Antibody Fab Fragment (PABJ-0145-F(E)) (PABJ-0145-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib, FuncS
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Recombinant Anti-FZD5 Vesicular Antibody, EV Displayed (VS-0425-YC416) (VS-0425-YC416)
- Species Reactivity: Human
- Target: FZD5
- Host Animal: Human
- Application: ELISA, FC, Inhib, Cell-uptake
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For Research Use Only. Not For Clinical Use.

Background

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.

Protein class

G-protein coupled receptors

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Distal enterocytes, Hepatocytes, Undifferentiated cells, Muller glia cells, Intestinal goblet cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BEWO, CACO-2, Hep G2, NTERA-2)

Interaction

Binding of unsaturated fatty acid molecules (via FZ domain) promotes homodimerization (PubMed:28377511). Interacts with WNT2B (PubMed:12490564). Interacts with WNT7A (PubMed:18230341, PubMed:20530549). Interacts with GOPC (By similarity).

Molecular function

Developmental protein, G-protein coupled receptor, Receptor, Transducer

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