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GALR1

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
Protein class

G-protein coupled receptors

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Early spermatids, Oligodendrocyte precursor cells, Enteroendocrine cells, Respiratory ciliated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Molecular function

G-protein coupled receptor, Receptor, Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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