Plasma proteins
Intracellular
Low cell type specificity
Immune cell enhanced (basophil)
Low cell line specificity
Can form homodimers and probably homotetramers (PubMed:17640864). Interacts with COPG1; the interaction is independent on ARF1 activation (PubMed:19039328). Interacts with ARF1, ARF3, ARF4 and ARF5 (PubMed:15616190, PubMed:17956946). Interacts with RAB1B (GTP-bound form); required for GBF1 membrane association (PubMed:17429068). Interacts with GGA1, GGA2 and GGA3 (PubMed:17666033). Interacts with USO1 (PubMed:12634853). Interacts (via SEC7 domain) with PNPLA2 (via C-terminus); the interaction is direct (PubMed:21789191). Interacts with ARMH3 (PubMed:31519766). (Microbial infection) Interacts with poliovirus protein 3A.
Guanine-nucleotide releasing factor
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For Research Use Only. Not For Clinical Use.