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GC
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein class
Metabolic proteins, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Group enriched (Hepatocytes, Cholangiocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HL-60, RH-30, SiHa, U-698)
Interaction
Associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Interacts with LRP2; the interaction is required for renal uptake of GC in complex with 25-hydroxyvitamin D3 (By similarity).
Molecular function
Actin-binding
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, IHC-P
- Mouse Anti-GC Recombinant Antibody (clone 7B11) (MOB-1693z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
-
- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, FC
- Chicken Anti-GC Polyclonal IgY (BRD-0955MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.