+ Filter
Loading...
GSDMD
Loading...Anti-GSDMD Products
- Rabbit Anti-GSDMD Recombinant Antibody (VS3-FY2724) (VS3-FY2724)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
Compare
- Anti-GSDMD Immunohistochemistry Kit (VS-0325-XY957)
-
- Species Reactivity: Human, Mouse, Rat
- Target: GSDMD
- Application: IHC
Compare
- Rabbit Anti-GSDMD Recombinant Antibody (VS13-YC476) (VS13-YC476)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Protein class
Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Distal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
[Gasdermin-D, N-terminal]: Homooligomer; homooligomeric ring-shaped pore complex containing 27-28 subunits when inserted in the membrane (PubMed:33883744). In response to a canonical inflammasome stimulus, such as nigericin, recruited to NLRP3 inflammasone with similar kinetics to that of uncleaved CASP1 precursor (By similarity). Although this recruitment is also observed in the absence of PYCARD, it is more efficient in its presence (By similarity).
More Types Infomation