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GSN
Loading...Anti-GSN Products
- Mouse Anti-GSN Recombinant Antibody (clone 33A5) (MOB-2035z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, ICC, IF, IHC
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- Rabbit Anti-GSN Recombinant Antibody (clone JB36-68) (MRO-0645-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Rabbit Anti-GSN Recombinant Antibody (clone R06-2I7) (VS3-FY1726)
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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- Camelid Anti-GSN Recombinant Single Domain Antibody (NBD-0041-YJ-VHH) (NBD-0041-YJ-VHH)
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA, IF, Inhib
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: BL, ELISA, IP, IHC, WB
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- Mouse Anti-GSN Recombinant Antibody (clone 5E3B9) (VS7-HM1051)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, FCM
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- Anti-GSN Immunohistochemistry Kit (VS-0525-XY2946)
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- Species Reactivity: Human
- Target: GSN
- Application: IHC
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- Anti-Mouse GSN Immunohistochemistry Kit (VS-0525-XY2947)
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- Species Reactivity: Human, Mouse
- Target: GSN
- Application: IHC
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- Anti-Bovine GSN Immunohistochemistry Kit (VS-0525-XY2948)
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- Species Reactivity: Human, Mouse, Rat, Bovine, Sheep
- Target: GSN
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Fibroblasts, Adipocytes)
Immune cell specificity
Immune cell enhanced (eosinophil)
Cell line specificity
Cell line enhanced (ASC diff, HaCaT)
Interaction
Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN AND TMSB4X. Interacts with the inactive form of EIF2AK2/PKR (By similarity).
Molecular function
Actin capping, Actin-binding
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