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GUCY1A2
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene.
Protein class
Enzymes, FDA approved drug targets, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Excitatory neurons, Oligodendrocyte precursor cells, Inhibitory neurons, Smooth muscle cells, Sertoli cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, TIME)
Interaction
Heterodimer of an alpha and a beta chain.
Molecular function
Lyase
More Types Infomation
- Recombinant Anti-Human GUCY1A2 Antibody (MOB-3444z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IF, FuncS
- Recombinant Anti-Human GUCY1A2 Antibody scFv Fragment (MOB-3444z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, FC, FuncS
- Recombinant Anti-Human GUCY1A2 Antibody Fab Fragment (MOB-3444z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, FACS, FuncS
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For Research Use Only. Not For Clinical Use.