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GYPE

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For Research Use Only. Not For Clinical Use.


Background

The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Predicted location

Membrane

Single cell type specificity

Cell type enriched (Erythroid cells)

Immune cell specificity

Immune cell enhanced (memory B-cell)

Cell line specificity

Group enriched (HEL, K-562)

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