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Target
Application
Host
Type
Species Reactivity
Conjugate
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HGF

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For Research Use Only. Not For Clinical Use.


Background

HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
HGF
Protein class

Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, RAS pathway related proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Fibroblasts, Muller glia cells, Smooth muscle cells, Hepatic stellate cells, Endometrial stromal cells)

Immune cell specificity

Immune cell enriched (basophil)

Cell line specificity

Cell line enhanced

Interaction

Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.

Molecular function

Growth factor, Serine protease homolog

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