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HGFAC

This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants.
Protein class

Cancer-related genes, Enzymes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Late spermatids, Early spermatids, Hepatocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (Hep G2)

Interaction

Heterodimer of a short chain and a long chain linked by a disulfide bond.

Molecular function

Hydrolase, Protease, Serine protease

More Types Infomation

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