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ID1
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Protein class
Cancer-related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Hepatic stellate cells, Adipocytes, Basal respiratory cells)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enhanced (EFO-21, HaCaT, Hep G2, PC-3)
Interaction
Heterodimer with other HLH proteins. Interacts with COPS5, IFI204, GATA4 and NKX2-5 (By similarity). Interacts with CLOCK and ARNTL/BMAL1.
Molecular function
Developmental protein, Repressor
More Types Infomation
- Rabbit Anti-ID1 Recombinant Antibody (clone JM92-13) (MRO-0808-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
-
- Derivation: Phage display library
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-ID1 Recombinant Antibody (clone 29D9) (MOB-3006z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, IF, IHC, IP
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
- Rabbit Anti-ID1 Recombinant Antibody (clone R01-2A4) (VS3-XY3390)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, ICC, IF, FC
- Rabbit Anti-Id1 Recombinant Antibody (clone #BCH-1/#37-2); scFv Fragment (HPAB-0418-CN-S(P))
-
- Species Reactivity: Mouse
- Type: Rabbit scFv
- Application: WB, ELISA, IHC
- Rabbit Anti-Id1 Recombinant Antibody (clone #BCH-1/#37-2) (HPAB-0418-CN)
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: WB, ELISA, IHC
- Rabbit Anti-Id1 Recombinant Antibody (clone #BCH-1/#37-2); Fab Fragment (HPAB-0418-CN-F(E))
-
- Species Reactivity: Mouse
- Type: Rabbit Fab
- Application: WB, ELISA, IHC
- Rabbit Anti-ID1 Recombinant Antibody (clone #BCH-1/#195-14) (HPAB-0309-YC)
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: ELISA, WB, IHC
- Rabbit Anti-ID1 Recombinant Antibody (clone #BCH-2/#5-3) (HPAB-0307-YC)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IHC
- Rabbit Anti-ID1 Recombinant Antibody (clone #BCH-1/#195-14); scFv Fragment (HPAB-0309-YC-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Rabbit scFv
- Application: ELISA, WB, IHC
- Rabbit Anti-ID1 Recombinant Antibody (clone #BCH-2/#5-3); scFv Fragment (HPAB-0307-YC-S(P))
-
- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, WB, IHC
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: ELISA, WB, IF
- Rabbit Anti-ID1 Recombinant Antibody (clone #BCH-1/#195-14); Fab Fragment (HPAB-0309-YC-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Rabbit Fab
- Application: ELISA, WB, IHC
- Rabbit Anti-ID1 Recombinant Antibody (clone #BCH-2/#5-3); Fab Fragment (HPAB-0307-YC-F(E))
-
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, WB, IHC
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