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ID4
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Endometrial ciliated cells, Muller glia cells, Smooth muscle cells, Endometrial stromal cells, Glandular and luminal cells, Breast myoepithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, AN3-CA, EFO-21, HEK93, SCLC-21H, SuSa)
Interaction
Heterodimer with other HLH proteins.
Molecular function
Repressor
More Types Infomation