Loading...
IFNGR1
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
Protein class
CD markers, Disease related genes, FDA approved drug targets, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Basal respiratory cells, Club cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Monomer (PubMed:9367779). Heterodimer with IFNGR2, to form the IFNG receptor complex (PubMed:7615558). Interacts with JAK1 (PubMed:7615558). Interacts (when phosphorylated) with STAT1 (PubMed:8156998). Interacts with SOCS1 (By similarity).
Molecular function
Receptor
More Types Infomation
Related Diseases
Maturity Onset Diabetes of the Young
- Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38); Fab Fragment (FAMAB-0193CQ-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, RIA
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC
- Rabbit Anti-IFNGR1 Antibody (clone GR20), mRNA (FAMAB-1381CQ-mRNA)
-
- Species Reactivity: Mouse
- Mouse Anti-IFNGR1 Antibody (clone gamma R99), mRNA (FAMAB-0194CQ-mRNA)
-
- Species Reactivity: Human
- Mouse Anti-IFNGR1 Antibody (clone gamma R38), mRNA (FAMAB-0193CQ-mRNA)
-
- Species Reactivity: Human
- Rabbit Anti-IFNGR1 Recombinant Antibody (clone GR20) (FAMAB-1381CQ)
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: Block, Neut, FC
- Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R99); scFv Fragment (FAMAB-0194CQ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, RIA
- Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38); scFv Fragment (FAMAB-0193CQ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, RIA
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: Neut
- Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R99) (FAMAB-0194CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, RIA
- Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38) (FAMAB-0193CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, RIA
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: Neut
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, FC, IHC
- Rat Anti-Ifngr1 Recombinant Antibody (clone mAb0830) (NEUT-1043CQ)
-
- Species Reactivity: Mouse
- Type: Rat IgG2
- Application: Block, FC
- Rat Anti-Ifngr1 Recombinant Antibody (clone CBL577) (NEUT-1042CQ)
-
- Species Reactivity: Mouse
- Type: Rat IgG2b
- Application: ELISA, Neut
- Rat Anti-Ifngr1 Recombinant Antibody (clone GR-20) (NEUT-1041CQ)
-
- Species Reactivity: Mouse
- Type: Rat IgG2a, κ
- Application: FC, FuncS, Neut
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, Neut, FC
- Mouse Anti-IFNGR1 Recombinant Antibody (clone CBL509) (NEUT-1039CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, CyTOF, Neut
- Mouse Anti-IFNGR1 Recombinant Antibody (clone GIR 208) (NEUT-1038CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IP, Block, IHC, WB
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, Neut, WB
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.