+ Filter
Loading...
Custom Services order now ship next day

Anti-IGF1R Recombinant Antibody Products

Anti-IGF1R Recombinant Antibody Products

  • IGF1-DT immunotoxin (AGTO-L024D)
    • Species Reactivity: Human
    • Application: Cytotoxicity assay, Functional assay
    Go to compare Compare
  • IGF1-PE immunotoxin (AGTO-L024E)
    • Species Reactivity: Human
    • Application: Cytotoxicity assay, Functional assay
    Go to compare Compare

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Creative Biolabs globally provides a wide range of high-quality anti-IGF1R recombinant antibodies. These antibodies are precisely produced through advanced biotechnological procedures to assure maximum performance in a variety of research applications. Our cutting-edge platform leverages the most recent advances in antibody engineering and production, ensuring superior specificity, stability, and effectiveness. Furthermore, our experienced staff is dedicated to serving the scientific community by offering both high-quality products and outstanding customer service. We provide individual advice and technical knowledge to help researchers optimize their experimental designs and achieve their research objectives.

IGF1R: A Key Target for Cancer Therapy

The development and metastasis of cancer are significantly influenced by the insulin-like growth factor (IGF) axis. Among its constituents, the type 1 IGF receptor (IGF-1R) stands out as a critical component, known for its cancer-promoting actions across several cancer types. Specifically, IGF-1R promotes tumor development, metastasis, and resistance to cancer therapy. Given its importance in cancer etiology, IGF-1R is seen as a prospective target for cancer therapeutic development.

Alternative Names

Insulin-like growth factor 1 (IGF-1) receptor; insulin like growth factor 1 receptor; IGF-1R; CD221; IGFIR; IGFR; JTK13.

Background

This receptor binds insulin-like growth factors with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively, spliced transcript variants encoding distinct isoforms have been found for this gene.

Anti-IGF1R rAb Products

Creative Biolabs provides a wide range of recombinant anti-IGF1R antibodies that have been rigorously developed to provide maximum specificity and affinity. These antibodies are available in a variety of forms, each designed to assist a wide range of research and therapeutic goals, from fundamental studies to the development of breakthrough healthcare products. We employ our sophisticated platform to deliver breakthrough tools that drive research in immunology, cancer biology, and related domains, as well as accelerate the advancement of therapeutic innovation.

Table 1. Featured anti-IGF1R recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
TAB-199 Human Anti-IGF1R Recombinant Antibody (TAB-199) Human Human IgG1, κ FC, IP, ELISA, Neut, FuncS, IF, ICC, Inhib, WB, Activ, IHC, Block
TAB-736 Anti-IGF1R Recombinant Antibody (Dalotuzumab) Human Mouse IgG1 - kappa FC, IP, ELISA, Neut, FuncS, IF, ICC, WB, Activ, Inhib
TAB-014ZJ Mouse Anti-IGF1R Recombinant Antibody (TAB-014ZJ) Human Mouse IgG1 ELISA, FC, Inhib, IP
TAB-078 Anti-Human IGF1 Receptor Recombinant Antibody (Cixutumumab) Human Human IgG1 - lambda IP, Neut, FuncS, ELISA, FC, WB, IHC, Stim, IF, Block
TAB-052ZJ Anti-Human IGF-1R Recombinant Antibody (18) Human Human antibody IHC, ELISA, FC, IF, IP

Creative Quality Control

Creative Biolabs provides an extensive range of rigorously tested anti-IGF1R recombinant antibodies. Our advanced facilities and skilled scientists meticulously develop each antibody to precisely target IGF1R, and we conduct thorough testing and validation to ensure that these antibodies display exceptional specificity, robust binding affinity, and optimal properties for diverse research applications.

Fig.1 ELISA analysis. (Creative Biolabs Original)Fig.1 ELISA analysis of anti-IGF1R antibody
(Cat# TAB-199, Creative Biolabs).

Fig.2 HPLC analysis. (Creative Biolabs Original)Fig.2 HPLC analysis of anti-IGF1R antibody
(Cat# TAB-014ZJ, Creative Biolabs).

Fig.3 WB analysis. (Creative Biolabs Original)Fig.3 WB analysis of anti-IGF1R antibody
(Cat# TAB-078, Creative Biolabs).

Fig.4 WB analysis. (Creative Biolabs Original)Fig.4 WB analysis of anti-IGF1R antibody
(Cat# TAB-199, Creative Biolabs).

Customer Reviews

Excellent
Ji**e
Human Anti-IGF1R Recombinant Antibody (TAB-199) (TAB-199)
In multiple experiments, Creative Biolabs' anti-IGF1R antibody showed amazing stability and consistency, which greatly improved our research efficiency. We are very satisfied with the reliability of the experimental results, which is undoubtedly the best decision we made in antibody selection.
21/Oct/2021
Excellent
Ro***t
Mouse Anti-IGF1R Recombinant Antibody (TAB-014ZJ) (TAB-014ZJ)
In addition to the first-class product quality, Creative Biolabs' customer support is also excellent. During the use of antibodies, we can get professional technical support and help at any time, which makes our research progress smoother and more efficient.
17/Jun/2022
Excellent
User 180*****23
Anti-Human IGF-1R Recombinant Antibody (6E11c) (TAB-085ZJ)
I've been utilizing Creative Biolabs' anti-IGF1R recombinant antibodies for my research projects, and I must say, their performance has been outstanding. The antibodies demonstrate exceptional specificity and strong binding affinity, which has significantly enhanced the accuracy and reliability of my experiments. Additionally, the level of consistency and stability observed across various tests has been impressive, facilitating smoother progress in my research. I highly recommend their products to any researcher looking for reliable and high-quality antibodies!
22/Nov/2023

rAb Production

Creative Biolabs provides an excellent supply of high-quality anti-IGF1R antibodies generated through cutting-edge genetic techniques.

Featured Anti-IGF1R Recombinant Antibody Production PlatformsFig.5 Milligram-scale anti-IGF1R rAb. (Creative Biolabs Original)
Fig.5 Milligram-scale anti-IGF1R recombinant antibody production.

Fig.6 Gram-scale anti-IGF1R rAb. (Creative Biolabs Original)Fig.6 Gram-scale anti-IGF1R recombinant antibody production.

rAb Modalities

Creative Biolabs delivers a broad selection of top-tier anti-IGF1R recombinant antibodies in various formats, catering to the diverse needs of researchers worldwide.

Fig.7 Full-length anti-IGF1R rAb. (Creative Biolabs Original)Fig.7 Full-length anti-IGF1R recombinant antibody production and modalities.

IGF1R-Targeted Drug Information

Table 2. Public drug targeting IGF1R.

Company Research Phase Classification Condition
Amgen
Chugai Pharmaceutical
Genmab (Originator)
Horizon Pharma (Amgen)
Horizon Therapeutics (Amgen)
River Vision (Amgen)
Roche
Launched - 2020 Cancer Immunotherapy
Human Monoclonal Antibodies
Cancer
Cancer, breast
Cancer, breast, metastatic
Cancer, lung (non-small cell) (NSCLC)
Cancer, solid tumor
Diabetic macular edema
Sarcoma
Thyroid-associated ophthalmopathy (Graves ophthalmopathy)
Astellas Pharma (Originator)
Fujisawa (Astellas Pharma)
OrphanPacific
Launched - 1995 Insulin-Like Growth Factor-1 (IGF-1)
Polypeptides, from 41 AA
Recombinant proteins
Diabetes
Growth hormone deficit
Biogen (Originator)
Pfizer (Originator)
Registered - 1994 Insulin-Like Growth Factor-1 (IGF-1)
Polypeptides, from 41 AA
Recombinant proteins
Diabetes
Innovent Biologics (Originator) Pre-Registered Monoclonal Antibodies Autoimmune disease
Thyroid-associated ophthalmopathy (Graves ophthalmopathy)
Cephalon (Teva)
Chiron (Novartis Vaccines and Diagnostics)
Kyowa Kirin
Novartis Vaccines and Diagnostics
Teva (Originator)
Pre-Registered Insulin-Like Growth Factor-1 (IGF-1)
Polypeptides, from 41 AA
Recombinant proteins
Amyotrophic lateral sclerosis
Osteoarthritis
Other neurological disorders
Amgen (Originator)
Cancer International Research Group
Dana-Farber Cancer Institute
ImmunityBio
NantCell (ImmunityBio)
National Cancer Institute
National Cancer Institute (NCI) (National Cancer Institute)
Takeda
Phase III Cancer Immunotherapy
Human Monoclonal Antibodies
Cancer
Cancer, breast
Cancer, colorectal, metastatic
Cancer, lung (small cell) (SCLC)
Cancer, ovary
Cancer, ovary (epithelial)
Cancer, pancreas (adenocarcinoma)
Cancer, pancreas (adenocarcinoma) metastatic
Cancer, pancreas, metastatic
Cancer, solid tumor
Neuroendocrine cancer
Non-Hodgkin lymphoma
Rhabdomyosarcoma
Sarcoma, Ewing
Soft tissue sarcoma
ImmunoGen (Originator)
Sanofi
sanofi-aventis (Sanofi)
Viridian Therapeutics
Zenas BioPharma
Phase III Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer
Cancer, breast
Cancer, liver
Cancer, solid tumor
Multiple myeloma
Thyroid-associated ophthalmopathy (Graves ophthalmopathy)
Memorial Sloan-Kettering Cancer Center
Merck & Co
Merck & Co. (Merck & Co)
Pierre Fabre (Originator)
Phase II/III Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer
Cancer, breast
Cancer, colorectal, metastatic
Cancer, lung (non-small cell) (NSCLC)
Cancer, pancreas (adenocarcinoma)
Multiple myeloma
Neuroendocrine cancer
ImVax
Thomas Jefferson University (Originator)
Phase II Antisense Therapy
Cancer Immunotherapy
Cancer Vaccines
Cell Therapy
Single-stranded oligodeoxyribonucleotide (DNA)
Astrocytoma
Cancer, brain
Glioblastoma
Glioma
ImClone (Lilly)
Lilly (Originator)
National Cancer Institute
National Cancer Institute (NCI) (National Cancer Institute)
National Cancer Institute (US) (National Cancer Institute)
University of Chicago
University of Washington
Phase II Cancer Immunotherapy
Human Monoclonal Antibodies
Acute lung injury
Cancer, breast
Cancer, breast, metastatic
Cancer, colorectal, metastatic
Cancer, esophagus
Cancer, head and neck
Cancer, head and neck (squamous cell carcinoma)
Cancer, liver
Cancer, liver (hepatocellular carcinoma)
Cancer, lung (non-small cell) (NSCLC)
Cancer, lung (non-small cell) (NSCLC), metastatic
Cancer, lung (small cell) (SCLC)
Cancer, pancreas
Cancer, pancreas, metastatic
Cancer, prostate, metastatic
Cancer, solid tumor
Cancer, thymus
Fibrosis
Lymphoma
Melanoma, uveal
Mesothelial tumor
Neuroendocrine cancer
Sarcoma
Soft tissue sarcoma

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

As a leading provider of biotechnology research services, Creative Biolabs is dedicated to offering an extensive array of premium anti-IGF1R recombinant antibodies. For further details or inquiries about our products, feel free to reach out to us at your convenience.

  • 0
  • 0
Cart
    Go to compare

    Go to compare