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IGHA1
Contributes to immunoglobulin receptor binding activity. Involved in antibacterial humoral response; glomerular filtration; and positive regulation of respiratory burst. Located in extracellular space. Part of monomeric IgA immunoglobulin complex and secretory dimeric IgA immunoglobulin complex.
Protein class
Disease related genes, Immunoglobulin genes
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Group enriched (Plasma cells, B-cells)
Immune cell specificity
Group enriched (memory B-cell, naive B-cell)
Cell line specificity
Cell line enhanced (HDLM-2, RPMI-8226, SH-SY5Y, U-266/70, U-266/84)
Interaction
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked (PubMed:20176268). Monomeric or polymeric (PubMed:2241915). Part of the secretory IgA (sIgA) complex that consists of two, four or five IgA monomers, and two additional non-Ig polypeptides, namely the JCHAIN and the secretory component (the proteoytic product of PIGR).
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-IGHA1 Recombinant Antibody (clone 3-B6) (MRO-0817-CN)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IHC, ELISA
- Mouse Anti-IGHA1 Recombinant Antibody (clone 5-C3) (MRO-0816-CN)
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, IHC, ELISA
- Mouse Anti-IGHA1 Recombinant Antibody (clone A10-B5) (MRO-0815-CN)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ELISA
- Mouse Anti-IGHA1 Recombinant Antibody (clone C9-G3) (MRO-0814-CN)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ELISA
- Rabbit Anti-IGHA1 Recombinant Antibody (clone JM10-42) (MRO-0813-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, ICC, IF, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgM
- Application: WB
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
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