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IGHG4

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For Research Use Only. Not For Clinical Use.


IGHG4 (Immunoglobulin Heavy Constant Gamma 4 (G4m Marker)) is a Protein Coding gene. Among its related pathways are Creation of C4 and C2 activators and Role of phospholipids in phagocytosis. Gene Ontology (GO) annotations related to this gene include antigen binding. An important paralog of this gene is IGHG2.
Protein class

FDA approved drug targets, Immunoglobulin genes, Plasma proteins

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Group enriched (Plasma cells, B-cells)

Immune cell specificity

Group enriched (memory B-cell, naive B-cell)

Cell line specificity

Cell line enriched (RPMI-8226)

Interaction

Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked.

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