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For Research Use Only. Not For Clinical Use.


Background

Enables several functions, including coreceptor activity; hedgehog family protein binding activity; and heparin binding activity. Involved in several processes, including maintenance of protein location in extracellular region; regionalization; and smoothened signaling pathway. Located in cell surface; cytoneme; and plasma membrane. Is expressed in several structures, including dorsal epidermis primordium; embryonic anal pad; embryonic dorsal epidermis; embryonic epipharynx; and imaginal disc. Human ortholog(s) of this gene implicated in holoprosencephaly 11. Orthologous to human BOC (BOC cell adhesion associated, oncogene regulated) and CDON (cell adhesion associated, oncogene regulated). [provided by Alliance of Genome Resources, Feb 2025]
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