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IL31

Anti-IL31 Products

Afuco™ Anti-Human IL31 ADCC Recombinant Antibody (BMS-981164), ADCC Enhanced (AFC-409CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Mouse Anti-IL31 Recombinant Antibody (VMC200) (NEUT-1385CQ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut
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Afuco™ Anti-IL31 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-419CQ) (AFC-TAB-419CQ)
- Derivation: Caninized
- Species Reactivity: Canine
- Type: ADCC enhanced antibody
- Application: ELISA, IHC, FC, IP, IF, FuncS
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Recombinant Anti-IL31 Eliminating Antibody, pH-Sensitive (VS-0625-YC185) (VS-0625-YC185)
- Species Reactivity: Canine
- Type: Canine IgG2 kappa
- Application: Antigen-Sweeping In Vivo.
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For Research Use Only. Not For Clinical Use.

Background

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.