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IL32
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- PE-A*24:02/Human IL32 (YYEEQHPEL) MHC Tetramer (MHC-LC2378)
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- Class: Class I
- Antigen: IL32
- Antigen Species: Human
- Peptide: YYEEQHPEL
- Conjugate: PE
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Protein class
Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Proximal tubular cells, Pancreatic endocrine cells, T-cells, Ductal cells, Exocrine glandular cells)
Immune cell specificity
Immune cell enhanced (T-reg)
Cell line specificity
Cell line enhanced (CACO-2, CAPAN-2, HDLM-2, Hep G2, Karpas-707, MOLT-4, RH-30, U-937)
Molecular function
Cytokine
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