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IRAK2

Anti-IRAK2 Products

Recombinant Mouse anti-Human IRAK2 Monoclonal antibody (FQ3904Z) (MOB-2270CT)
- Species Reactivity: Human
- Application: ELISA, WB
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Recombinant Rabbit Anti-IRAK2 Monoclonal Antibody (JG36-23) (MRO-0865-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC, IP
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Rabbit Anti-IRAK2 Recombinant Antibody (clone JG36-23) (VS3-WK460)
- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ELISA
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Anti-IRAK2 Immunohistochemistry Kit (VS-0525-XY3581)
- Species Reactivity: Human
- Target: IRAK2
- Application: IHC
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For Research Use Only. Not For Clinical Use.

IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.

Protein class

Enzymes, Human disease related genes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Langerhans cells, Oligodendrocytes, Urothelial cells, Prostatic glandular cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (BEWO, BJ hTERT+, CAPAN-2, GAMG, RT4)

Interaction

Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

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Related Signaling Pathways

TLR Signaling Pathway