Cancer-related genes, Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Inhibitory neurons, Oligodendrocytes)
Not detected in immune cells
Cell line enhanced (HEK93, NTERA-2, RT4, WM-115)
Interacts with SOCS6 in response to stimulation with either insulin or IGF1 (By similarity). Interacts with CRK and CRKL. Interaction with CRK is stronger than with CRKL. Interacts with CRK via the phosphorylated YXXM motifs. Interacts with GRB2 and PIK3R1. Interacts with PLC-gamma, SHC1, PTK6, PPP4C and NISCH.
Transducer
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For Research Use Only. Not For Clinical Use.