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ITGB8

Anti-ITGB8 Products
- Mouse Anti-ITGB8 Recombinant Antibody (HPAB-0400-WJ) (HPAB-0400-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody (HPAB-0401-WJ) (HPAB-0401-WJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Recombinant Mouse Anti-Human ITGB8 Antibody (MOB-2027MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- A*02:01/Human ITGB8 (ALMEQQHYV) MHC Pentamer (MHC-YF505)
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- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: Unlabeled, Biotin, R-PE, APC
- PE-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0917)
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- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: PE
- APC-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0918)
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- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: APC
- FITC-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0919)
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- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: FITC
- A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0920)
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- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: Unconjugated
- Mouse Anti-ITGB8 Recombinant Antibody; Fab Fragment (HPAB-0400-WJ-F(E)) (HPAB-0400-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody; Fab Fragment (HPAB-0401-WJ-F(E)) (HPAB-0401-WJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody; scFv Fragment (HPAB-0400-WJ-S(P)) (HPAB-0400-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody; scFv Fragment (HPAB-0401-WJ-S(P)) (HPAB-0401-WJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Target: ITGB8
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
- Chicken Anti-ITGB8 Polyclonal IgY (BRD-0303MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Protein class
Cancer-related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Endometrial ciliated cells, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enhanced (AF22, EFO-21, RPTEC TERT1, WM-115)
Interaction
Heterodimer of an alpha and a beta subunit (PubMed:1918072). Beta-8 (ITGB8) associates with alpha-V (ITGAV) to form ITGAV:ITGB8 (PubMed:1918072, PubMed:22278742). ITGAV:ITGB8 interacts with TGFB1 (PubMed:22278742).
Molecular function
Integrin, Receptor
More Types Infomation