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Itgam

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This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Species Reactivity:
Mouse
Type:
Llama VHH
Application:
CA, IP, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
BL
Species Reactivity:
Human
Type:
IgG1
Application:
FC, IHC-Fr, BL
Species Reactivity:
Human
Type:
IgG1, κ
Application:
FC, FuncS, IP, Neut
Species Reactivity:
Mouse
Type:
IgG2a, κ
Application:
FC, ICC, IP, BL
Species Reactivity:
Mouse, Rabbit, Human, Chimpanzee, Baboon, Cynomolgus monkey
Type:
IgG2b, κ
Application:
ICC/IF, FC, FuncS, BL
Species Reactivity:
Mouse
Type:
IgG2b
Application:
BL, FC, IHC-Fr, IP, WB
Species Reactivity:
Mouse
Type:
IgG2b
Application:
BL
Type:
scFv
Application:
WB
Type:
Fab
Application:
WB
Species Reactivity:
Human
Type:
Mouse IgG2b
Application:
IHC, IF, FC
Type:
IgG
Application:
IF, IHC-Fr
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
BL
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Species Reactivity:
Human
Type:
Mouse antibody
Application:
ELISA
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
BL
Species Reactivity:
Human, Rat, Mouse
Type:
Chicken antibody
Application:
ICC/IF
Application:
WB
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, ELISA, FuncS
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