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KCNJ12
Anti-KCNJ12 Recombinant Antibody Products
- Rabbit Anti-Kcnj12 Recombinant Antibody (VS-0522-LC132) (VS-0522-LC132)
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- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: WB
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- Rat Anti-Kcnj12 Recombinant Antibody (VS-0522-LC131) (VS-0522-LC131)
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- Species Reactivity: Rat
- Type: Rat IgG2b
- Application: WB
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- Mouse Anti-Kcnj12 Recombinant Antibody (VS-0522-LC130) (VS-0522-LC130)
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- Species Reactivity: Rat
- Type: Mouse IgG2a
- Application: WB
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For Research Use Only. Not For Clinical Use.
Kcnj12 (Potassium Inwardly Rectifying Channel Subfamily J Member 12) is a Protein Coding gene. This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current. Diseases associated with Kcnj12 include Smith-Magenis Syndrome and Andersen Cardiodysrhythmic Periodic Paralysis.
Protein class
FDA approved drug targets, Transporters, Voltage-gated ion channels
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Horizontal cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (EFO-21, HeLa, PC-3, SCLC-21H, SiHa, SuSa, U-2197)
Interaction
Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking (By similarity). Homotetramer. Forms heteromer with KCNJ4.
Molecular function
Ion channel, Voltage-gated channel
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