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KIF6
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For Research Use Only. Not For Clinical Use.
Background
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Oligodendrocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (GAMG, RPMI-8226, SCLC-21H, SK-MEL-30)
Molecular function
Motor protein
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