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KRT2

Anti-KRT2 Products
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-KRT2 Recombinant Antibody (VS3-FY2757) (VS3-FY2757)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ICC, FC, ELISA
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- Species Reactivity: Human
- Application: WB, IHC-P, IHC-Fr
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P
- Anti-KRT2 Immunohistochemistry Kit (VS-0325-XY1215)
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- Species Reactivity: Human, Mouse, Rat
- Target: KRT2
- Application: IHC
- Mouse Anti-KRT2 Recombinant Antibody (clone 1A2B5) (VS7-0425-WR262)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, IHC, ICC, FC
- Mouse Anti-KRT2 Recombinant Antibody (clone 8A1E1) (VS7-0425-WR263)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: IHC, ICC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Suprabasal keratinocytes)
Immune cell specificity
Immune cell enhanced (naive CD4 T-cell)
Cell line specificity
Cell line enhanced (HEL)
Interaction
Heterotetramer of two type I and two type II keratins. Associates with KRT10 (By similarity).
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