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Kit & VCAM-1

Anti-Kit & VCAM-1 Products
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- Species Reactivity: Human
- Application: IHC, WB
- Recombinant Mouse Anti-KIT Antibody (12A8) (NEUT-1632CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: WB, IP, FC, Neut
- Recombinant Rat Anti-Kit Antibody (ACK2) (NEUT-1633CQ)
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- Species Reactivity: Mouse
- Type: IgG2b, κ
- Application: FC, BL, Depletion
- Human Anti-KIT Recombinant Antibody (TAB-470CL) (TAB-470CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, WB
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- Type: Mouse IgG2b
- Application: ELISA, ICC, FC
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- Type: Mouse IgG1
- Application: ELISA, FC
- AbPlus™ Anti-Kit Magnetic Beads (VS-0724-YC1349) (VS-0724-YC1349)
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- Target: Kit
- Target Species: Mouse
- Application: IP, Protein Purification
- Mouse Anti-KIT Recombinant Antibody (HPAB-1952-FY) (HPAB-1952-FY)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
- Mouse Anti-KIT Antibody (clone Kit2C75), mRNA (FAMAB-0024-CN-mRNA)
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- Species Reactivity: Chicken
- Human Anti-KIT Antibody (clone Fab19), mRNA (PABL-255-mRNA)
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- Species Reactivity: Human
- Mouse Anti-KIT Recombinant Antibody (clone 8D7) (VS3-XY973)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF
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- Species Reactivity: Human
- Type: Mouse IgG1
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- Species Reactivity: Human
- Type: Mouse IgG1
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF
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- Type: Mouse IgG2b
- Application: ELISA, ICC, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgM
- Application: WB, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IF, FC
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- Species Reactivity: Human
- Type: Mouse IgM, κ
- Application: WB, IHC-P
- Rabbit Anti-KIT Recombinant Antibody (VS3-CJ575) (VS3-CJ575)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
- Mouse Anti-KIT Antibody (TAB-467LC), mRNA (TAB-467LC-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC-P, IF, WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ICC, IHC
- Human Anti-KIT Recombinant Antibody (HPAB-1950-FY) (HPAB-1950-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
- Mouse Anti-KIT Recombinant Antibody (HPAB-1951-FY) (HPAB-1951-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody (HPAB-1949-FY) (HPAB-1949-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
- Human Anti-KIT Recombinant Antibody (HPAB-1948-FY) (HPAB-1948-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
- Human Anti-KIT Recombinant Antibody (HPAB-1947-FY) (HPAB-1947-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
- Human Anti-KIT Recombinant Antibody (HPAB-1570-FY) (HPAB-1570-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, Inhib
- Human Anti-KIT Recombinant Antibody (HPAB-1571-FY) (HPAB-1571-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody (HPAB-1572-FY) (HPAB-1572-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
- Rabbit Anti-KIT Polyclonal Antibody (MRO-1775-CN) (MRO-1775-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, FC
- Mouse Anti-KIT Recombinant Antibody (HPAB-N0156-YC) (HPAB-N0156-YC)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody (HPAB-N0157-YC) (HPAB-N0157-YC)
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized IgG1
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody (HPAB-3398LY) (HPAB-3398LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody (HPAB-3399LY) (HPAB-3399LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody (HPAB-0019-FY) (HPAB-0019-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG1, κ
- Application: FC
- Mouse Anti-KIT Recombinant Antibody (clone 21G5) (MOB-1436z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IHC, WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
- Recombinant Mouse Anti-KIT Antibody (CBL158) (NEUT-1634CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Mouse Anti-KIT Recombinant Antibody (clone Kit2C75) (FAMAB-0024-CN)
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- Derivation: Mouse
- Species Reactivity: Chicken
- Type: Mouse IgG
- Application: FC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
- Recombinant Mouse Anti-KIT Antibody (A3C6E2) (NEUT-1629CQ)
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- Species Reactivity: Human
- Type: IgG1, κ
- Application: FC, BL
- Recombinant Mouse Anti-KIT Antibody (CBL788) (NEUT-1630CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: WB, FC, CyTOF, ELISA(Cap), Neut
- Recombinant Mouse Anti-KIT Antibody (14G5) (NEUT-1631CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Anti-Human KIT Recombinant Antibody scFv Fragment (TAB-467LC-S(P)) (TAB-467LC-S(P))
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- Application: WB
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-0019-FY-S(P)) (HPAB-0019-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized scFv
- Application: FC
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-0019-FY-F(E)) (HPAB-0019-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
- Human Anti-KIT Recombinant Antibody scFv Fragment (HPAB-3398LY-S(P)) (HPAB-3398LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody scFv Fragment (HPAB-3399LY-S(P)) (HPAB-3399LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody Fab Fragment (HPAB-3398LY-F(E)) (HPAB-3398LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, WB
- Mouse Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-N0156-YC-S(P)) (HPAB-N0156-YC-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-N0157-YC-S(P)) (HPAB-N0157-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized scFv
- Application: ELISA, Inhib, FuncS
- Mouse Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-N0156-YC-F(E)) (HPAB-N0156-YC-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, Inhib, FuncS
- Mouse Anti-KIT Recombinant Antibody (clone Kit2C75); scFv Fragment (FAMAB-0024-CN-S(P))
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- Derivation: Mouse
- Species Reactivity: Chicken
- Type: Mouse scFv
- Application: FC
- Mouse Anti-KIT Recombinant Antibody (clone Kit2C75); Fab Fragment (FAMAB-0024-CN-F(E))
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- Derivation: Mouse
- Species Reactivity: Chicken
- Type: Mouse Fab
- Application: FC
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1570-FY-F(E)) (HPAB-1570-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1571-FY-F(E)) (HPAB-1571-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-N0157-YC-F(E)) (HPAB-N0157-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized Fab
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1947-FY-F(E)) (HPAB-1947-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody Fab Fragment (HPAB-3399LY-F(E)) (HPAB-3399LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1948-FY-F(E)) (HPAB-1948-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1948-FY-S(P)) (HPAB-1948-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized scFv
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1949-FY-F(E)) (HPAB-1949-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1572-FY-F(E)) (HPAB-1572-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1570-FY-S(P)) (HPAB-1570-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1571-FY-S(P)) (HPAB-1571-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1572-FY-S(P)) (HPAB-1572-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
- Mouse Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1951-FY-F(E)) (HPAB-1951-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1947-FY-S(P)) (HPAB-1947-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized scFv
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1950-FY-F(E)) (HPAB-1950-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1950-FY-S(P)) (HPAB-1950-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized scFv
- Application: Block, ELISA, FC, IF
- Mouse Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1951-FY-S(P)) (HPAB-1951-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1949-FY-S(P)) (HPAB-1949-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized scFv
- Application: Block, ELISA, FC, IF
- Mouse Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1952-FY-F(E)) (HPAB-1952-FY-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: Block, ELISA, FC, IF
- Mouse Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1952-FY-S(P)) (HPAB-1952-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block, ELISA, FC, IF
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC, IF
- Mouse Anti-NHP KIT Recombinant Antibody (clone 104D2) (VS-1024-XY127)
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- Species Reactivity: Bovine, Human, Non-human primate
- Type: Mouse IgG1, kappa
- Application: FC
- Anti-cKIT (clone 9P3)-SMCC-DM1 ADC (ADC-094CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKIT (clone NEG085)-SMCC-DM1 ADC (ADC-095CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKIT (clone NEG024)-SMCC-DM1 ADC (ADC-096CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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- Species Reactivity: Human, Cynomolgus
- Target: KIT
- Host Animal: Mouse
- Application: ELISA, FC, Inhib, Cell-uptake
- Anti-KIT Immunohistochemistry Kit (VS-0525-XY3787)
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- Species Reactivity: Human
- Target: KIT
- Application: IHC
- Anti-Mouse KIT Immunohistochemistry Kit (VS-0525-XY3788)
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- Species Reactivity: Human, Mouse, Porcine
- Target: KIT
- Application: IHC
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- Antibody Host: Human
- Antibody Reactivity: Human
- CytoStream™ Mouse Anti-KIT Recombinant Antibody (clone 104D2) (VS-0225-XY154)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
- CytoStream™ Rat Anti-KIT Recombinant Antibody (clone ACK45) (VS-0225-XY155)
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- Species Reactivity: Mouse
- Type: Rat IgG2b, kappa
- Application: FC
- Human Anti-KIT scFv-Fc Chimera (VS-0325-FY38) (VS-0325-FY38)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: Inhib, FC
- Mouse Anti-KIT Monoclonal Antibody (clone 1C5) (VS7-0425-WR221)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
- Mouse Anti-KIT Monoclonal Antibody (VS7-0425-WR222) (VS7-0425-WR222)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ELISA
- Chicken Anti-KIT Polyclonal IgY (BRD-0316MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Derivation: Phage display library screening
- Type: IgG
- Application: IHC-P, IHC-Fr
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- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, ICC
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- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, ICC, FC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
The protein encoded by this gene is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.