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Kit & VCAM-1
Loading...Anti-Kit & VCAM-1 Products
- Recombinant Mouse Anti-KIT Antibody (12A8) (NEUT-1632CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: WB, IP, FC, Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, FuncS
- Human Anti-KIT Recombinant Antibody (TAB-470CL) (TAB-470CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
- Recombinant Rat Anti-Kit Antibody (ACK2) (NEUT-1633CQ)
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- Species Reactivity: Mouse
- Type: IgG2b, κ
- Application: FC, BL, Depletion
- Anti-Human KIT Recombinant Antibody (TAB-467LC) (TAB-467LC)
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- Application: WB
- Human Anti-KIT Recombinant Antibody (TAB-468LC) (TAB-468LC)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, FuncS
- Human Anti-KIT Recombinant Antibody; Fab Fragment (TAB-468LC-F(E)) (TAB-468LC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, WB, ELISA
- AbPlus™ Anti-Kit Magnetic Beads (VS-0724-YC1349) (VS-0724-YC1349)
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- Target: Kit
- Target Species: Mouse
- Application: IP, Protein Purification
- Human Anti-KIT Recombinant Antibody (HPAB-1571-FY) (HPAB-1571-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody (HPAB-1947-FY) (HPAB-1947-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
- Mouse Anti-KIT Recombinant Antibody (clone 21G5) (MOB-1436z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IHC, WB
- Human Anti-KIT Recombinant Antibody (TAB-466LC) (TAB-466LC)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, SPR
- Recombinant Mouse Anti-KIT Antibody (CBL158) (NEUT-1634CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Human Anti-KIT Recombinant Antibody; Fab Fragment (TAB-466LC-F(E)) (TAB-466LC-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: FC, WB, SPR, ELISA
- Human Anti-KIT Recombinant Antibody (HPAB-1570-FY) (HPAB-1570-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, Inhib
- Human Anti-KIT Recombinant Antibody (HPAB-0019-FY) (HPAB-0019-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG1, κ
- Application: FC
- Human Anti-KIT Recombinant Antibody (HPAB-3398LY) (HPAB-3398LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
- Mouse Anti-KIT Recombinant Antibody (clone Kit2C75) (FAMAB-0024-CN)
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- Derivation: Mouse
- Species Reactivity: Chicken
- Type: Mouse IgG
- Application: FC
- Mouse Anti-KIT Recombinant Antibody (HPAB-N0156-YC) (HPAB-N0156-YC)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody (HPAB-N0157-YC) (HPAB-N0157-YC)
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized IgG1
- Application: ELISA, Inhib, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-KIT Recombinant Antibody; scFv Fragment (TAB-468LC-S(P)) (TAB-468LC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC, WB, ELISA
- Human Anti-KIT Recombinant Antibody; Fab Fragment (TAB-465LC-F(E)) (TAB-465LC-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: FC, WB, SPR, ELISA
- Recombinant Mouse Anti-KIT Antibody (CBL788) (NEUT-1630CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: WB, FC, CyTOF, ELISA(Cap), Neut
- Recombinant Mouse Anti-KIT Antibody (14G5) (NEUT-1631CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Human Anti-KIT Recombinant Antibody (TAB-465LC) (TAB-465LC)
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, SPR
- Human Anti-KIT Recombinant Antibody; scFv Fragment (TAB-466LC-S(P)) (TAB-466LC-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: FC, WB, SPR, ELISA
- Human Anti-KIT Recombinant Antibody; scFv Fragment (TAB-465LC-S(P)) (TAB-465LC-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: FC, WB, SPR, ELISA
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, WB
- Recombinant Mouse Anti-KIT Antibody (A3C6E2) (NEUT-1629CQ)
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- Species Reactivity: Human
- Type: IgG1, κ
- Application: FC, BL
- Human Anti-KIT Recombinant Antibody (HPAB-1572-FY) (HPAB-1572-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody (HPAB-3399LY) (HPAB-3399LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IF, FC
- Mouse Anti-KIT Recombinant Antibody (HPAB-1952-FY) (HPAB-1952-FY)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
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- Species Reactivity: Human
- Type: Mouse IgM, κ
- Application: WB, IHC-P
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
- Human Anti-KIT Recombinant Antibody (HPAB-1948-FY) (HPAB-1948-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
- Rabbit Anti-KIT Recombinant Antibody (VS3-CJ575) (VS3-CJ575)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
- Human Anti-KIT Recombinant Antibody (HPAB-1949-FY) (HPAB-1949-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
- Human Anti-KIT Recombinant Antibody (HPAB-1950-FY) (HPAB-1950-FY)
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized IgG
- Application: ELISA, FC, Inhib
- Mouse Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1951-FY-S(P)) (HPAB-1951-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1948-FY-S(P)) (HPAB-1948-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized scFv
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1949-FY-S(P)) (HPAB-1949-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized scFv
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1949-FY-F(E)) (HPAB-1949-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1948-FY-F(E)) (HPAB-1948-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized Fab
- Application: Block, ELISA, FC, IF
- Mouse Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1952-FY-F(E)) (HPAB-1952-FY-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1571-FY-S(P)) (HPAB-1571-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
- Anti-Human KIT Recombinant Antibody scFv Fragment (TAB-467LC-S(P)) (TAB-467LC-S(P))
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- Application: WB
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
- Mouse Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-N0156-YC-S(P)) (HPAB-N0156-YC-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-N0157-YC-S(P)) (HPAB-N0157-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized scFv
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-N0157-YC-F(E)) (HPAB-N0157-YC-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized Fab
- Application: ELISA, Inhib, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
- Mouse Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-N0156-YC-F(E)) (HPAB-N0156-YC-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, Inhib, FuncS
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1571-FY-F(E)) (HPAB-1571-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
- Anti-Human KIT Recombinant Antibody Fab Fragment (TAB-467LC-F(E)) (TAB-467LC-F(E))
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- Application: WB
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-0019-FY-S(P)) (HPAB-0019-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized scFv
- Application: FC
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1570-FY-F(E)) (HPAB-1570-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA
- Mouse Anti-KIT Recombinant Antibody (clone Kit2C75); scFv Fragment (FAMAB-0024-CN-S(P))
-
- Derivation: Mouse
- Species Reactivity: Chicken
- Type: Mouse scFv
- Application: FC
- Human Anti-KIT Recombinant Antibody scFv Fragment (HPAB-3399LY-S(P)) (HPAB-3399LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1947-FY-F(E)) (HPAB-1947-FY-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-0019-FY-F(E)) (HPAB-0019-FY-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1572-FY-S(P)) (HPAB-1572-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1947-FY-S(P)) (HPAB-1947-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human, Canine, Monkey
- Type: Humanized scFv
- Application: Block, ELISA, FC, IF
- Mouse Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-1951-FY-F(E)) (HPAB-1951-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Block, ELISA, FC, IF
- Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-1570-FY-S(P)) (HPAB-1570-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA
- Human Anti-KIT Recombinant Antibody scFv Fragment (HPAB-3398LY-S(P)) (HPAB-3398LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody Fab Fragment (HPAB-3399LY-F(E)) (HPAB-3399LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, WB
- Human Anti-KIT Recombinant Antibody Fab Fragment (HPAB-3398LY-F(E)) (HPAB-3398LY-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, WB
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- Species Reactivity: Chicken
- Type: Mouse IgG
- Application: FC
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- Derivation: Phage display library screening
- Type: IgG
- Application: IHC-P, IHC-Fr
- Mouse Anti-KIT Monoclonal Antibody (clone 1C5) (VS7-0425-WR221)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
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- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, ICC
- Anti-cKIT (clone 9P3)-SPDB-DM4 ADC (ADC-102CL)
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- Target: cKIT
- Linker: SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate)
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-cKIT (clone 9P3)-CX1-1-DM1 ADC (ADC-103CL)
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- Target: cKIT
- Linker: CX1-1 (2,5-dioxopyrrolidin-1-yl 17-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5,8,11,14-tetraoxo-4,7,10,13-tetraazaheptadecan-1-oate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKit-maitansine ADC (LOP628) (ADC-L039)
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- Target: cKit
- Linker: non-cleavable linker
- Drug: maitansine
- Anti-cKIT (clone NEG027)-SMCC-DM1 ADC (ADC-101CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Chicken Anti-KIT Polyclonal IgY (BRD-0316MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Targets: Kit & VCAM-1
- Type: CrossMab
- Application: FuncS, Promising therapeutic agent
- Anti-cKIT (clone 9P3)-SMCC-DM1 ADC (ADC-094CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKIT (clone NEG085)-SMCC-DM1 ADC (ADC-095CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKIT (clone NEG024)-SMCC-DM1 ADC (ADC-096CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKit-Maytansine ADC (ADC-039LZY)
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- Target: cKit
- Linker: non-cleavable linker
- Drug: Maytansine
- Anti-cKIT (clone 20376)-SMCC-DM1 ADC (ADC-097CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKIT (clone NEG086)-SMCC-DM1 ADC (ADC-098CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKIT (clone NEG087)-SMCC-DM1 ADC (ADC-099CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-cKIT (clone NEG026)-SMCC-DM1 ADC (ADC-100CL)
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- Target: cKIT
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Mouse Anti-KIT Monoclonal Antibody (VS7-0425-WR222) (VS7-0425-WR222)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-P, IF, ELISA
- Anti-KIT Antibody Prodrug, Protease Activated (Fab19) (VS-1025-YC213)
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- Species Reactivity: Human
- Host Animal: Human
- Target: KIT
- Application: ISZ, Cyt, FuncS
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- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, ICC, FC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
The protein encoded by this gene is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.


